Leveraging functional genomics to reveal novel targets for cancer treatment
- Terminas
- 2027-09-16
- Atidaryta
- 2027-02-10
- Biudžetas
- 115 323 812 €
- Tipas
- grant
Aprašymas
Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards and contribute to all of the following expected outcomes:Researchers and health professionals gain a deeper understanding of the functional effects of tumour heterogeneity during cancer initiation and progression, supporting the identification of more precise and novel therapeutic targets. Researchers, health professionals and innovators benefit from improved knowledge and tools to support the discovery and development of next generation genomically-informed cancer treatments.Researchers, innovators, and professionals across disciplines and sectors contribute to the UNCAN.eu research data platform by ensuring data interoperability, and enabling sustainable access to newly developed digital tools and models for the analysis and management of multimodal clinical data. Scope:The proposed topic will contribute to the EU Cancer Mission objective of improving the understanding of cancer initiation and progression. Of particular interest for this topic are paediatric and adolescent cancers[1] , cancers with limited treatment options, refractory cancers, rare cancers or cancer types with low five-year survival rates. Proposals may include the design of exploratory mechanistic studies using longitudinal patient bio-samples, clinical proof-of-concept studies and/or observational and translational studies involving newly collected or existing data, as appropriate. Applicants
Tinkamumas (iš šaltinio)
General conditions1. Admissibility conditions: Proposal page limit and layoutdescribed in Annex A and Annex E of the Horizon Europe Work Programme General Annexes.Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.2. Eligible countriesdescribed in Annex B of the Work Programme General Annexes.A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.3. Other Eligibility ConditionsSubject to restrictions for the protection of European communication networks.described in Annex B of the Work Programme General Annexes.4. Financial and operational capacity and exclusiondescribed in Annex C of the Work Programme General Annexes.5a. Evaluation and award: Award criteria, scoring and thresholdsdescribed in Annex D of the Work Programme General Annexes.5b. Evaluation and award: Submission and evaluation processesThe thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold is 12.described in Annex F of the Work Programme General Annexes and the Online Manual.5c. Evaluation and award: Indicative timeline for evaluation and grant agreementdescribed in Annex F of the Work Programme General Annexes.6. Legal and financial set-up of the grantsThe granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.described in Annex G of the Work Programme General Annexes.Specific conditions described in the specific topic of the Work Programme Application and evaluation forms and model grant agreement (MGA): Application form templatesPlease use the application form that you will find in the Submission System. You can find examples of standard application forms in the Reference Documents page.Evaluation form templates — will be used with the necessary adaptationsStandard evaluation form (HE RIA, IA) GuidanceHE Programme Guide Model Grant Agreements (MGA)HE MGA Call-specific instructions Information on clinical studies (HE) Additional documents: HE Main Work Programme 2026-2027 – 1. General IntroductionHE Main Work Programme 2026-2027 – 12. MissionsHE Main Work Programme 2026-2027 – 15. General AnnexesHE Framework Programme and Rules for Participation Regulation 2021/695HE Specific Programme Decision 2021/764EU Financial Regulation 2024/2509Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity AssessmentEU Grants AGA — Annotated Model Grant AgreementFunding & Tenders Portal Online ManualFunding & Tenders Portal Terms and Conditions Funding & Tenders Portal Privacy Statement
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